Volume 34, June 2024

Introduction

Letter from the Editors

Mohammed Abdullah, MD and Eric Schweppe, MD

Letter from the Chair: Building on a Legacy of Excellence

L. Scott Levin, MD, FACS, FAOA

Letter from the Program Director

Daniel C. Farber, MD

A Letter of Gratitude and Anticipation: Welcoming Dr. B. Kyle Potter as Our New Chairman

Jean-Claude G. D’Alleyrand, MD

Dedication: Dr. Eric Hume, MD

Joseph Bernstein, MD

Fostering Excellence: The UPOJ’s Impact on Orthopaedic Editors Through the Years

Mohammed Abdullah, MD and Eric Schweppe, MD

Department Updates

Spine Division Update
Amrit Khalsa, MD

Hand Division Update
David J. Bozentka, MD

Shoulder and Elbow Division Update
David L. Glaser, MD

Adult Reconstruction Division Update
Charles L. Nelson, MD

Foot and Ankle Division Update
Keith Wapner, MD

Orthopaedic Oncology Division Update
Cara A. Cipriano, MD, MSc

Orthoplastic Limb Salvage Division
Benjamin Gundlach, MD and L. Scott Levin, MD, FACS

Children’s Hospital of Philadelphia Update
Jack Flynn, MD, Ryan Quinn, MHA, and Divya Talwar, PhD, MPH

Health System Updates

Corporal Michael J. Crescenz Veterans Affairs Medical Center Update
Jean Claude D’Alleyrand, MD

Pennsylvania Hospital Update
Neil Sheth, MD

Penn Center for Musculoskeletal Disorders Update
Louis J. Soslowsky, PhD

Clinical Research Section Update
Annamarie D. Horan, MPA, PhD

Penn Achilles Tendinopathy Center of Research Translation
Louis J. Soslowsky, PhD

Resident and Fellow Updates

Current Residents

Clinical Research

Trauma

Tips and Tricks: Utilization of an Articulated Tensioning Device to Treat a Humeral Shaft Nonunion: Technical Considerations and Case Example
Lisa G. M. Friedman, MD, MA, Stephen Barchick, MD, Chielozor Okafor, MD, Bradley Osemwen

Management of a Multiply-Injured Patient with a Diaphyseal Tibial Fracture: Case Report and Technical Tips for Traveling Traction
Chielozor I. Okafor, MD, Bradley O. Osemwengie, MD, Lisa G.M. Friedman, MD, MA, Jordan S. Cohen, MD, Stephen R. Barchick, MD, Derek J. Donegan, MD, MBA

Spine

Tips and Tricks: Lumbar Spinal Peri-implant Lucency with Spontaneous Resolution— A Decision to Stay the Course
Bradley Osemwengie, MD, Tensae Assefa, MD, Chinedu Okafor, MD, Jennifer X. Hong, BA, Harvey Smith, MD

Recurrent Delayed Surgical Site Infections in Adolescent Idiopathic Scoliosis
Bradley Osemwengie, MD, Caroline Granruth, MD, Tensae Assefa, MD, Amrit Khalsa, MD

Trans-endplate Diffusion Across the Spectrum of Human Disc Degeneration
Brianna S. Orozco, BS, Sarah E. Gullbrand, PhD

Dropped Head Syndrome: A Case of Post-Surgical Distal Junctional Kyphosis and Chronic Infection
Bradley Osemwengie, MD, Jennifer X. Hong, BA, Tensae Assefa, MD, Chinedu Okafor, MD, Amrit Khalsa, MD

Sports

Tips & Tricks: Use of a Spinal Needle for Partial Meniscectomy of a Bucket Handle Meniscus Tear
Caroline Granruth, MD MPH, Heather Kellett, MD, Sand Mastrangelo, MD, Brian Sennett, MD

Motion Analysis and Biomechanical Evaluation Following Anterior Cruciate Ligament Reconstruction
Kevin M. Landrum, BS, David P. VanEenenaam, BS, Elliot Greenberg, PT, DPT, PhD, Valentina Graci, PhD, Theodore J. Ganley, MD

Is writing style associated with peer reviewer recommendations?
George E. Sayegh, BS, Amelia E. Mercado, BSA, Jacob E. Thomas, MA, David Ring, MD, PhD, Tom J. Crijns MD

Hand

Tips & Tricks: Closed Reduction of Pediatric Distal Radius Fractures in the Emergency Department
Ellis Berns, MD, Thompson Zhuang, MD MBA, Apurva Shah, MD MBA

Subcondylar Fossa Reconstruction: Outcomes in Pediatric Patients following Malunion of Proximal Phalanx Fractures
David P. VanEenenaam Jr., BS, Sarah L. Struble, BS, Eliza Buttrick, BA, Benjamin Chang, MD, Apurva S. Shah, MD MBA

Shoulder and Elbow

Tips & Tricks: Arthroscopic Shoulder Arthrodesis in Young Patients with Brachial Plexus Injuries: Restoration of Shoulder Stability for Hand Positioning
Erin A. Hale, MD, Brett J. Croen, MD, L. Scott Levin, MD, David L. Glaser, MD

Use of Internal Joint Stabilizer after Transradial Amputation and Elbow Instability: A Case Report
Madison Craft, MD and Brian Chenoweth, MD

Foot and Ankle

Tips and Tricks: Minimally Invasive Surgery with Transverse Osteotomy for Hallux Valgus Correction
Emily S. Eiel, MD, Lorraine A. T. Boakye, MD

Don’t Forget to Evaluate the Ankle—Tips and Tricks for Operative Treatment of Distal Third Tibia Fractures
Bradley O. Osemwengie, MD, Chielozor I. Okafor, MD, Lisa G.M. Friedman, MD, MA, Stephen R. Barch

Tendon Loads Measured over 2 Weeks of Daily Living are Associated with Achilles Tendinopathy Patient Outcomes
Ke Song, PhD, Michelle P. Kwon, BS, Andrew K. Smith, PT, DPT, MS, Karin Grävare Silbernagel, PT, ATC, PhD, FAPTA, Josh R. Baxter, PhD

Evidence of a Loose Total Ankle After Tibial Intramedullary Nail Insertion
Bradley Osemwengie, MD, Tensae Assefa, MD, Casey Jo Humbyrd, MD, MBE

Oncology

Tips and Tricks: Initial Management of Unknown Soft Tissue Masses
Maxwell Cardwell, MD, Jaret Karnuta, MD, MS, Cara Cipriano, MD

Orthoplastics

Tips and Tricks: Latissimus Dorsi Free Flap for Tumor-related Soft Tissue defects: A Case Report
Tensae Assefa, MD, Sand Mastrangelo, MD, Caroline Granruth, MD, Scott Levin, MD FACS, Cara Cipriano, MD

A Tale of Perseverance—A Ukrainian Soldier’s Fight to Keep His Arm After a Blast Injury
Bradley Osemwengie, MD, Chielozor Okafor, MD, Tyler Humphrey, MD, L. Scott Levin, MD

Arthoplasty

Tips and Tricks: Robotic-Assisted Total Knee Arthroplasty
Jaret M. Karnuta, MD, MS, Maxwell Cardwell, MD, Christopher Travers, MD

Medicare Payments May Inappropriately Favor Hemiarthroplasty Over Total Hip Arthroplasty for Geriatric Hip Fracture Treatment
Pranav Kodali, BA, Eric Hume, MD, Joseph Bernstein, MD

Pediatrics

A Distal Humerus Fracture with a Proximal Medial Forearm Wound- Open or Closed?
Bradley O. Osemwengie, MD, Chielozor I. Okafor, MD, Jacob Jordan, BA/BS, J. Todd R. Lawrence, MD/PhD

Management of Osteonecrosis of the Humeral Head in the Pediatric Population: A Systematic Review
Vineet Desai, BS, Akbar N. Syed, MD, Morgan Batley, BA, Lawrence Wells, MD, Brendan A. Williams, MD

Comparison between juvenile idiopathic arthritis and proliferative synovitis in children: Utility of contrast-enhanced MRI
Andressa Guariento MD, PhD, Vandan Patel, BS, David M. Biko, MD, Alyssa Sze, BA, Alexander Arkader, MD, Theodore J. Ganley, MD, Jie C. Nguyen, MD MS

Systematic Review of the Impact of Pelvic Obliquity in Patients with Neuromuscular Scoliosis
Joshua T. Bram, MD, Christopher J. DeFrancesco, MD, Tiffany C. Liu, MD, Waleed Al-Mahdi, MD, Keith D. Baldwin, MD, MPH, MSPT, David A. Spiegel, MD

Basic Science

Bone & Development

Exploring the Efficacy of Additively Manufactured PLGA Implants for Fracture Repair at Early Time Points
Kathryn S. Strand, BS, Anna N. Smith, BS, Joseph B. Ulsh, MS, Trent J. Levy, BS, Michael W. Hast, PhD

Imaging mass cytometry reveals distinct cellular phenotypes in CD14 deficient mouse synovium
Kevin G. Burt, Sanique M. South, Vu Nguyen, Lance A. Murphy, Robert L Mauck, Tim Griffin, Carla Scanzello

Conditional Deletion of PTH/PTHrP Receptor 1 in Osteocytes Abolishes Lactation-induced Alterations in Canalicular Pericellular Space and Increases Bone Microstructure Deterioration
Xiaoyu Xu, PhD, Yilu Zhou, PhD, Rosa M. Guerra, BS, Yongqiang Vincent Jin, MS, Yuanhang Li, MS, Wonsae Lee, PhD, Tala Azar, PhD, Kira Lu, Liyun Wang, PhD, X. Sherry Liu, PhD

Mechanical Properties of 3D Printed Clavicles are Closer to Cadaveric Bones than 4th Generation Sawbones
Kathryn S. Strand, BS, Elizabeth Silvestro, MS, Iman Naqvi, Michael W. Hast, PhD

Cartilage, Meniscus & Disc

In Situ and In Vivo Mechanoactivation of Anti-Inflammatory Tension-Activated Repair Patches
Mohammed S. Abdullah, Bijan Dehghani, Caitlin Barrett, Kevin G. Burt, Robert L Mauck, Thomas P. Schaer, Harvey E. Smith, Sarah E. Gulbrand

Viscous Hyaluronic Acid Carriers Enhance the Stability of Therapeutic Mechanically-Activated Microcapsules
Austin C. Jenk, BS, Eric A. Schweppe, MD, Elisabeth A. Lemmon, BS, Sarah E. Gullbrand, PhD, Robert L. Mauck, PhD

CD14 inhibition as a potential therapeutic for posttraumatic osteoarthritis.
Kevin G. Burt, Vu Nguyen, Lance A. Murphy, Robert L. Mauck, Anne-Marie Malfait, Rachel E. Miller, Carla R. Scanzello

Healing Of Partial-Thickness Cartilage Injuries in the Immature Skeleton: Development of a Large Animal Model for Pediatric Cartilage Research
Brendan D. Stoeckl, Elisabeth A. Lemmon, Jie C. Nguyen, Bijan Dehghani, Vandan Patel, Carlos Yaya, Robert L. Mauck, Theodore J. Ganley, Soroush Baghdadi

Osteochondral Defect Repair of Large Weight-Bearing Surfaces in a Porcine Model
Brendan D. Stoeckl, Kendall M. Masada, Axel C. Moore, Natalie L. Fogarty, Elisabeth A. Lemmon, Bijan Dehghani, Lorielle G. Laforest, James L. Carey, Robert L. Mauck, Molly M. Stevens, David R. Steinberg

Sustained Structural and Functional Deficits in the Porcine Knee Six Months Following Meniscus Destabilization
Stoeckl BD, Ching S, Nadruz V, McGroary O, Boyes M, Laforest L, Teinturier T, Zgonis MH, Elliott DM, Mauck RL, Hast MW, Schaer TP, Steinberg DR

Characterizing Discogenic Cell Based Tissue Engineered Disc Replacements
Matthew Fainor, BS, Galina Dulatova, PhD, Sage Frehner, MS, Harvey E. Smith, MD, Robert L. Mauck, PhD, William L. Heaton, MS, Sarah E. Gullbrand, PhD

Innervation and Inflammation Correlate with Structural and Mechanical Changes in a Large Animal Model of Intervertebral Disc Degeneration
Kevin G. Burt, PhD, Caitlin Barrett, MD, Thomas P. Schaer, VMD, Harvey E. Smith, MD, Robert L. Mauck, PhD, Sarah E. Gullbrand

Micromechanics and Mechanoresponsivity of the Developing Porcine Meniscus
Meghan E. Kupratis, PhD, Yuqi Zhang, BS, Jiaqi Xiang, BS, Bryan Kwok, BS, Elisabeth A. Lemmon, VMD, Karen L. Xu, BS, Nathaniel A. Dyment, PhD, Lin Han, PhD, Eiki Koyama, PhD, Robert L. Mauck, PhD

Muscle, Tendon, and Ligament

An Automated Tracking Algorithm Characterizing Deformation of Fatigue-Induced Achilles Tendons
Sittinon Nuethong, MS, Todd J. Hullfish, BME, Josh R. Baxter, PhD

Comparing the Efficiency of Anterior Cruciate Ligament Reconstruction across Ambulatory Surgery Centers, a University Hospital, and a Hybrid Inpatient Hospital: A Prospective Study
Vineet Desai, BS, Morgan Swanson, BA, Divya Talwar, PhD, Alexandra Stevens, BS, Theodore J. Ganley, MD

Strain-Induced Collagen Fibril Deformation is Diminished with Advanced Age in Mouse Supraspinatus Tendon
Jeremy D. Eekhoff, Stephanie N. Weiss, Louis J. Soslowsky

Tendon-Targeted Collagen V Deficiency and Knockout Attenuate Mature Supraspinatus Tendon Mechanics
Michael S. DiStefano, Stephanie N. Weiss, Andrew F. Kuntz, Louis J. Soslowsky

Tendon-Targeted Collagen V Knockout Influences Mechanical Properties of Aged Supraspinatus Tendon
Mitchell J. Hallman, Michael S. DiStefano, Stephanie N. Weiss, Jeremy D. Eekhoff, Louis J. Soslowsky

Collagens V and XI Jointly Regulate Fibril Assembly and Elastic Mechanical Properties during Tendon Maturation
Nat A. Thurlow, Jeremy D. Eekhoff, Ashley K. Fung, Courtney A. Nuss, Stephanie N. Weiss, Nathaniel A. Dyment, Louis J. Soslowsky

Type III Collagen Expression Decreases During Neonatal Tendon Development and is Unchanged in Early Neonatal Tendon Healing
Margaret K. Tamburro, MS, Jaclyn A. Carlson, PhD, Miranda K. Doro, Stephanie N. Weiss, Susan W. Volk, VMD, PhD, Louis J. Soslowsky, PhD

Focal Adhesion Kinase Regulates Physiological Tendon Development and Growth
Thomas P. Leahy, Srish S. Chenna, Louis J. Soslowsky, Nathaniel A. Dymen

Non-Muscle Myosin II Knockdown Disrupts Tenocyte Morphology and Contractility
Elizabeth R. Bernstein, Mary Kate Evans, Xi Jiang, Timur B. Kamalitdinov, Robert L. Mauck, Nathaniel A. Dyment

Col1a1 Expression Decreases while Col3a1 Expression Increases after Neonatal Tendon Injury
Miranda K Doro, Margaret K Tamburro, MS, Jaclyn A Carlson, PhD, Susan W Volk, VMD, PhD, Louis J Soslowsky, PhD

High-Speed Treadmill Running Does Not Induce a Tendinopathic Phenotype in Rat Achilles Tendon
Snehal S. Shetye, PhD, Margaret K. Tamburro, MS, Ashley K. Fung, PhD, Thomas P. Leahy, PhD, Madison N. Magee, Harina A. Raja, MS, Stephanie N. Weiss, BS, Courtney A. Nuss, BS, Alexander J. Bein, Daniel C. Farber, MD, Louis J. Soslowsky, PhD